What is the impact of Advanced Glycation End Products (AGEs) on health?

Advanced Glycation End Products (AGEs) have a notable impact on health by inducing oxidative stress and promoting cell damage. AGEs are formed through the non-enzymatic reaction between sugars and proteins, lipids, or nucleic acids, particularly under conditions of high glucose levels. Once formed, AGEs can accumulate in various tissues in the body, leading to impaired cellular function.

The presence of AGEs is linked to the development and progression of various diseases, such as diabetes and cardiovascular diseases. They contribute to inflammation and oxidative stress, which can result in cellular damage and dysfunction. The process of oxidative stress involves the generation of free radicals that can harm cells, proteins, and DNA, leading to various pathological conditions.

Understanding the detrimental effects of AGEs emphasizes the importance of maintaining healthy blood sugar levels and a balanced diet to minimize their formation and accumulation in the body. Thus, the choice indicating that AGEs induce oxidative stress and promote cell damage accurately reflects the significant health risks associated with these compounds.