Which of the following population studies assessed the impact of diet on heart disease?

The Nurses' Health Study is particularly significant in assessing the impact of diet on heart disease because it was one of the largest and longest-running studies focused on women's health. Launched in 1976, this observational study included a cohort of registered nurses who provided extensive dietary information through detailed questionnaires. Researchers were able to analyze the relationship between dietary habits, lifestyle factors, and the incidence of cardiovascular disease among the participants over time.

This study has provided valuable insights into how various dietary patterns and specific nutrients can influence heart health, often indicating that diets rich in fruits, vegetables, and whole grains are associated with a lower risk of heart disease. Additionally, the extensive follow-up with participants allows for long-term observation of health outcomes related to dietary habits, making the findings robust and influential in the field of lifestyle medicine.

While the other studies listed also address health outcomes and have provided valuable data on various health aspects, the focus of the Nurses' Health Study on diet's direct correlation with heart disease is what makes it particularly relevant to this question.